What condition is characterized by changes in the distance or spacing in fingerprints?

The condition that is characterized by changes in the distance or spacing in fingerprints is acromegaly. This disorder results from excessive growth hormone, typically due to a pituitary adenoma, leading to abnormal growth of bones and tissues. One of the notable features of acromegaly is the enlargement of the hands and feet, which can also cause alterations in the patterns of fingerprints. As the fingers enlarge, the ridges and spaces between them may change, altering the overall fingerprint appearance.

Other conditions mentioned, like eczema and leprosy, primarily affect the skin's surface without causing significant changes in fingerprint patterns. Rickets results from a deficiency of Vitamin D, calcium, or phosphate, affecting bone development and possibly causing deformities, but it does not directly influence fingerprint spacing. Thus, acromegaly is distinctive for its physical effects on body structure, leading to changes in fingerprint characteristics.