Which method is noted for DNA extraction from the spleen?

The Galstun method is recognized for its effective application in DNA extraction from the spleen, particularly in forensic and biological studies. This method is notable for its ability to yield high-quality DNA from tissues that have less available cellular material, such as in cases of degraded samples or specific organ tissues. The technique employs specific lysis buffers and incubating conditions tailored to maximize the recovery of nucleic acids from the spleen.

In contrast, the Chomczynski method, while widely used for general DNA extraction, is more geared towards extracting DNA from cell cultures or blood and may not be specifically optimized for spleen tissue. Similarly, the DNeasy method is a popular choice for DNA isolation from a variety of biological samples but is more generalized and may not offer the specific enhancements required for the unique cellular architecture of the spleen. Finally, phenol-chloroform extraction is a traditional method used for DNA extraction but involves hazardous chemicals and can be less efficient in yielding DNA directly from spleen samples compared to techniques tailored for specific tissues.

The Galstun method is thus preferred in this context for DNA extraction from the spleen due to its targeted approach and effectiveness.