Which of the following is the antidote for Digoxin toxicity?

The antidote for Digoxin toxicity is Digoxin immune Fab, also known as Digibind. This specific antidote works by binding to Digoxin molecules in the bloodstream, forming a complex that is then excreted by the kidneys. By binding to Digoxin, Digibind reduces the free concentration of the drug in circulation, which helps to mitigate the toxic effects, such as arrhythmias and other life-threatening symptoms typically associated with Digoxin overdose.

In the management of Digoxin toxicity, other options such as activated charcoal may be used in certain situations, especially if the ingestion is recent, but they do not directly counteract the effects of Digoxin like Digibind does. N-acetylcysteine is primarily used for acetaminophen overdose and has no role in Digoxin toxicity. Sodium bicarbonate can be useful in treating certain types of metabolic acidosis and can help in cardiac issues related to other drug overdoses, but it is not effective for Digoxin toxicity. Thus, Digoxin immune Fab is the established and effective antidote in these cases.